Phase I Trial of Pyragrel, a Novel Thromboxane Synthetase Inhibitor, to Evaluate the Safety, Tolerability, and Pharmacokinetics in Healthy Volunteers
Background and Objective: Inhibition of thrombosis and platelet aggregation through a thromboxane synthetase inhibitor proved to be an effective and promising treatment for cardiovascular and/or cerebrovascular disease (CCVD) patients. This phase I study evaluated the safety, tolerability, and pharm...
Saved in:
Main Authors: | Chan Zou (Author), Xiaocong Zuo (Author), Jie Huang (Author), Ye Hua (Author), Shuang Yang (Author), Xiaoyan Yang (Author), Can Guo (Author), Hongyi Tan (Author), Jun Chen (Author), Zhaoxing Chu (Author), Qi Pei (Author), Guoping Yang (Author) |
---|---|
Format: | Book |
Published: |
Frontiers Media S.A.,
2019-10-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Semi-Mechanistic Modeling of HY-021068 Based on Irreversible Inhibition of Thromboxane Synthetase
by: Ping Li, et al.
Published: (2020) -
Thromboxane Modulates Endothelial Permeability
by: J. M. Klausner, et al.
Published: (1994) -
Measurement of Thromboxane Biosynthesis in Health and Disease
by: Carlo Patrono, et al.
Published: (2019) -
Foetal vascular responses to thromboxane receptor blockade
by: B. A. Meyer, et al.
Published: (1992) -
Phase 1 study to access safety, tolerability, pharmacokinetics, and pharmacodynamics of kynurenine in healthy volunteers
by: Mohammad Al‐Mahdi Al‐Karagholi, et al.
Published: (2021)