An In Vitro/In Vivo Model to Analyze the Effects of Flubendazole Exposure on Adult Female Brugia malayi.

• Main Authors: Maeghan O'Neill (Author), Abdelmoneim Mansour (Author), Utami DiCosty (Author), James Geary (Author), Michael Dzimianski (Author), Scott D McCall (Author), John W McCall (Author), Charles D Mackenzie (Author), Timothy G Geary (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Current control strategies for onchocerciasis and lymphatic filariasis (LF) rely on prolonged yearly or twice-yearly mass administration of microfilaricidal drugs. Prospects for near-term elimination or eradication of these diseases would be improved by availability of a macrofilaricide that is high...