New Insights into Osteogenic and Chondrogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells and Their Potential Clinical Applications for Bone Regeneration in Pediatric Orthopaedics

• Main Authors: Nicola Giuliani (Author), Gina Lisignoli (Author), Marina Magnani (Author), Costantina Racano (Author), Marina Bolzoni (Author), Benedetta Dalla Palma (Author), Angelica Spolzino (Author), Cristina Manferdini (Author), Caterina Abati (Author), Denise Toscani (Author), Andrea Facchini (Author), Franco Aversa (Author)
• Format: Book
• Published: Hindawi Limited, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Human mesenchymal stem cells (hMSCs) are pluripotent adult stem cells capable of being differentiated into osteoblasts, adipocytes, and chondrocytes. The osteogenic differentiation of hMSCs is regulated either by systemic hormones or by local growth factors able to induce specific intracellular sign...