Quantification and Evaluations of Catechin Hydrate Polymeric Nanoparticles Used in Brain Targeting for the Treatment of Epilepsy

• Main Authors: Niyaz Ahmad (Author), Rizwan Ahmad (Author), Ridha Abdullah Alrasheed (Author), Hassan Mohammed Ali Almatar (Author), Abdullah Sami Al-Ramadan (Author), Mohd Amir (Author), Md Sarafroz (Author)
• Format: Book
• Published: MDPI AG, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To formulate novel chitosan (CS)-coated−PLGA−nanoparticles (NPs) using a central composite design approach and use them in order to improve brain bioavailability for catechin hydrate (CH) through direct nose-to-central nervous system (CNS) delivery for the evaluation of a compara...