Formulation Development of Sublingual Cyclobenzaprine Tablets Empowered by Standardized and Physiologically Relevant Ex Vivo Permeation Studies

• Hauptverfasser: Haidara Majid (Verfasst von), Andreas Puzik (Verfasst von), Tanja Maier (Verfasst von), Raphaela Merk (Verfasst von), Anke Bartel (Verfasst von), Hans-Christian Mueller (Verfasst von), Bjoern B. Burckhardt (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2021-09-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Suitable ex vivo models are required as predictive tools of oromucosal permeability between in vitro characterizations and in vivo studies in order to support the development of novel intraoral formulations. To counter a lack of clinical relevance and observed method heterogenicity, a standardized,...