Orientia tsutsugamushi subverts dendritic cell functions by escaping from autophagy and impairing their migration.

• Main Authors: Ji-Hye Choi (Author), Taek-Chin Cheong (Author), Na-Young Ha (Author), Youngho Ko (Author), Chung-Hyun Cho (Author), Ju-Hong Jeon (Author), Insuk So (Author), In-Kyu Kim (Author), Myung-Sik Choi (Author), Ik-Sang Kim (Author), Nam-Hyuk Cho (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Dendritic cells (DCs) are the most potent antigen-presenting cells that link innate and adaptive immune responses, playing a pivotal role in triggering antigen-specific immunity. Antigen uptake by DCs induces maturational changes that include increased surface expression of major histoco...