Nrf2 Is a Key Regulator on Puerarin Preventing Cardiac Fibrosis and Upregulating Metabolic Enzymes UGT1A1 in Rats

• Main Authors: Shao-Ai Cai (Author), Ning Hou (Author), Gan-Jian Zhao (Author), Xia-Wen Liu (Author), Ying-Yan He (Author), Hai-Lin Liu (Author), Yong-Quan Hua (Author), Li-Rong Li (Author), Yin Huang (Author), Cai-Wen Ou (Author), Cheng-Feng Luo (Author), Min-Sheng Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Puerarin is an isoflavone isolated from Radix puerariae. Emerging evidence shown that puerarin possesses therapeutic benefits that aid in the prevention of cardiovascular diseases. In this study, we evaluated the effects of puerarin on oxidative stress and cardiac fibrosis induced by abdominal aorti...