Type XVIII collagen is essential for survival during acute liver injury in mice

• Main Authors: Michael B. Duncan (Author), Changqing Yang (Author), Harikrishna Tanjore (Author), Patrick M. Boyle (Author), Doruk Keskin (Author), Hikaru Sugimoto (Author), Michael Zeisberg (Author), Bjorn R. Olsen (Author), Raghu Kalluri (Author)
• Format: Book
• Published: The Company of Biologists, 2013-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

SUMMARY The regenerative response to drug- and toxin-induced liver injury induces changes to the hepatic stroma, including the extracellular matrix. Although the extracellular matrix is known to undergo changes during the injury response, its impact on maintaining hepatocyte function and viability i...