Protection of outbred mice against a vaginal challenge by a Chlamydia trachomatis serovar E recombinant major outer membrane protein vaccine is dependent on phosphate substitution in the adjuvant

• Main Authors: Sukumar Pal (Author), Salvador Fernando Ausar (Author), Delia F. Tifrea (Author), Chunmei Cheng (Author), Scott Gallichan (Author), Violette Sanchez (Author), Luis M. de la Maza (Author), Lucian Visan (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chlamydia trachomatis is the most common bacterial sexually-transmitted pathogen for which there is no vaccine. We previously demonstrated that the degree of phosphate substitution in an aluminum hydroxide adjuvant in a TLR-4-based C. trachomatis serovar E (Ser E) recombinant major outer membrane pr...