Silymarin protects mouse liver and kidney from thioacetamide induced toxicity by scavenging reactive oxygen species and activating PI3K-Akt pathway

• Главные авторы: Shatadal Ghosh (Автор), Abhijit Sarkar (Автор), Sudip Bhattacharyya (Автор), Parames C. Sil (Автор)
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• Опубликовано: Frontiers Media S.A., 2016-12-01T00:00:00Z.
• Предметы: article
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Abstract:Silymarin (SMN) has been shown to possess a wide range of biological and pharmacological effects. Besides, SMN has antioxidant and free radical scavenging activities. Thioacetamide (TAA) is a well-documented liver toxin that requires oxidative bioactivation to elicit its hepatotoxic effect...