Development of Diclofenac Sodium 3D Printed Cylindrical and Tubular-Shaped Tablets through Hot Melt Extrusion and Fused Deposition Modelling Techniques

• Main Authors: Tryfon Digkas (Author), Alina Porfire (Author), Jeroen Van Renterghem (Author), Aseel Samaro (Author), Gheorghe Borodi (Author), Chris Vervaet (Author), Andrea Gabriela Crișan (Author), Sonia Iurian (Author), Thomas De Beer (Author), Ioan Tomuta (Author)
• Format: Book
• Published: MDPI AG, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The present study aimed to develop 3D printed dosage forms, using custom-made filaments loaded with diclofenac sodium (DS). The printed tablets were developed by implementing a quality by design (QbD) approach. Filaments with adequate FDM 3D printing characteristics were produced via hot melt extrus...