Synergetic Effect of β-Cyclodextrin and Its Simple Carbohydrate Substituents on Complexation of Folic Acid and Its Structural Analog Methotrexate

• Principais autores: Magdalena Ceborska (Autor), Aleksandra Siklitskaya (Autor), Aneta Aniela Kowalska (Autor), Karolina Kędra (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2024-09-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Folic acid (FA) and its structural analog, anticancer medicine methotrexate (MTX), are known to form host/guest complexes with native cyclodextrins, of which the most stable are formed with the medium-sized β-cyclodextrin. Based on our research, proving that simple sugars (D-glucose, D-galactose, an...