Transcriptional and immunological analysis of the putative outer membrane protein and vaccine candidate TprL of Treponema pallidum.

• Main Authors: Austin M Haynes (Author), Mark Fernandez (Author), Emily Romeis (Author), Oriol Mitjà (Author), Kelika A Konda (Author), Silver K Vargas (Author), Maria Eguiluz (Author), Carlos F Caceres (Author), Jeffrey D Klausner (Author), Lorenzo Giacani (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>An effective syphilis vaccine should elicit antibodies to Treponema pallidum subsp. pallidum (T. p. pallidum) surface antigens to induce pathogen clearance through opsonophagocytosis. Although the combination of bioinformatics, structural, and functional analyses of T....