Broad-Spectrum In Vitro Activity of <i>N</i>α-Aroyl-<i>N</i>-Aryl-Phenylalanine Amides against Non-Tuberculous Mycobacteria and Comparative Analysis of RNA Polymerases

• मुख्य लेखकों: Markus Lang (लेखक), Uday S. Ganapathy (लेखक), Rana Abdelaziz (लेखक), Thomas Dick (लेखक), Adrian Richter (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2024-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

This study investigates the in vitro activity of <i>N</i>α-aroyl-<i>N</i>-aryl-phenylalanine amides (AAPs), previously identified as antimycobacterial RNA polymerase (RNAP) inhibitors, against a panel of 25 non-tuberculous mycobacteria (NTM). The compounds, including the hit...