Broad-Spectrum In Vitro Activity of <i>N</i>α-Aroyl-<i>N</i>-Aryl-Phenylalanine Amides against Non-Tuberculous Mycobacteria and Comparative Analysis of RNA Polymerases

• Päätekijät: Markus Lang (Tekijä), Uday S. Ganapathy (Tekijä), Rana Abdelaziz (Tekijä), Thomas Dick (Tekijä), Adrian Richter (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2024-04-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

This study investigates the in vitro activity of <i>N</i>α-aroyl-<i>N</i>-aryl-phenylalanine amides (AAPs), previously identified as antimycobacterial RNA polymerase (RNAP) inhibitors, against a panel of 25 non-tuberculous mycobacteria (NTM). The compounds, including the hit...