Simvastatin-Loaded Nanostructured Lipid Carriers as Topical Drug Delivery System for Wound Healing Purposes: Preparation, Characterization, and In Vivo Histopathological Studies

• Main Authors: Seyedeh Maryam Mousavi-Simakani (Author), Amir Azadi (Author), Nader Tanideh (Author), Navid Omidifar (Author), Parisa Ghasemiyeh (Author), Soliman Mohammadi-Samani (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: Simvastatin, a 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, is a commonly used drug to reduce total cholesterol and low-density lipoprotein (LDL) levels. Furthermore, several mechanisms showed the wound-healing potential of statins, especially simvastatin. Simvastati...