Effect of Erythropoietin on Angiogenesis With the Increased Adhesion of Platelets to the Microvessels in the Hind-Limb Ischemia Model in Mice

• Main Authors: Shintaro Kato (Author), Hideki Amano (Author), Yoshiya Ito (Author), Koji Eshima (Author), Naoyoshi Aoyama (Author), Hideaki Tamaki (Author), Hiroyuki Sakagami (Author), Yukitoshi Satoh (Author), Toru Izumi (Author), Masataka Majima (Author)
• Format: Book
• Published: Elsevier, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Erythropoietin (EPO) has been shown to enhance angiogenesis, but its precise mechanisms of enhancement during ischemia are not fully elucidated. We examined the effect of EPO on blood flow recovery from acute hind-limb ischemia induced by ligation of the femoral artery in male C57Bl/6 mice. The dens...