Anti-inflammatory, Analgesic, and Gastric Tissue Effects of Lacidipine, Aspirin, and Their Combination

• Main Authors: Bahar Isik (Author), Irem Ates (Author), Bahadir Suleyman (Author), Renad Mammadov (Author), Seval Bulut (Author), Mine Gulaboglu (Author), Adalet Ozcicek (Author), Halis Suleyman (Author)
• Format: Book
• Published: Polskie Towarzystwo Farmaceutyczne, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The increase in cyclooxygenase-2 (COX-2) activity and the decrease in COX-1 activity were associated with increased intracellular calcium. Lacidipine, a calcium channel blocker, can protect gastric tissue from aspirin-induced damage while potentiating the analgesic and anti-inflammatory properties o...