Abemaciclib-loaded ethylcellulose based nanosponges for sustained cytotoxicity against MCF-7 and MDA-MB-231 human breast cancer cells lines

• मुख्य लेखकों: Md. Khalid Anwer (लेखक), Farhat Fatima (लेखक), Mohammed Muqtader Ahmed (लेखक), Mohammed F. Aldawsari (लेखक), Amer S. Alali (लेखक), Mohd Abul Kalam (लेखक), Aws Alshamsan (लेखक), Musaed Alkholief (लेखक), Abdul Malik (लेखक), Alanazi Az (लेखक), Ramadan Al-shdefat (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2022-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abemaciclib (AC) is a novel, orally available drug molecule approved for the treatment of breast cancer. Due to its low bioavailability, its administration frequency is two to three times a day that can decrease patient compliance. Sustained release formulation are needed for prolong the action and...