Paclitaxel-Induced Endothelial Dysfunction in Living Rats Is Prevented by Nicorandil via Reduction of Oxidative Stress

• Auteurs principaux: Ken-ichi Serizawa (Auteur), Kenji Yogo (Auteur), Ken Aizawa (Auteur), Yoshihito Tashiro (Auteur), Yoko Takahari (Auteur), Kaori Sekine (Auteur), Toshihiko Suzuki (Auteur), Nobuhiko Ishizuka (Auteur), Hideyuki Ishida (Auteur)
• Format: Livre
• Publié: Elsevier, 2012-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Paclitaxel-eluting stents dramatically reduce rates of in-stent restenosis; however, paclitaxel is known to lead to endothelial dysfunction. Protective effects of nicorandil on paclitaxel-induced endothelial dysfunction by examining flow-mediated dilation (FMD) were investigated in anesthetized rats...