Paclitaxel-Induced Endothelial Dysfunction in Living Rats Is Prevented by Nicorandil via Reduction of Oxidative Stress

• প্রধান লেখক: Ken-ichi Serizawa (লেখক), Kenji Yogo (লেখক), Ken Aizawa (লেখক), Yoshihito Tashiro (লেখক), Yoko Takahari (লেখক), Kaori Sekine (লেখক), Toshihiko Suzuki (লেখক), Nobuhiko Ishizuka (লেখক), Hideyuki Ishida (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2012-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Paclitaxel-eluting stents dramatically reduce rates of in-stent restenosis; however, paclitaxel is known to lead to endothelial dysfunction. Protective effects of nicorandil on paclitaxel-induced endothelial dysfunction by examining flow-mediated dilation (FMD) were investigated in anesthetized rats...