Endothelin Type B Receptor-Induced Sustained Ca2+ Influx Involves Gq/11/Phospholipase C-Independent, p38 Mitogen-Activated Protein Kinase-Dependent Activation of Na+/H+ Exchanger

• Principais autores: Tsunaki Higa (Autor), Takahiro Horinouchi (Autor), Hiroyuki Aoyagi (Autor), Hiroshi Asano (Autor), Tadashi Nishiya (Autor), Arata Nishimoto (Autor), Ikunobu Muramatsu (Autor), Soichi Miwa (Autor)
• Formato: Livro
• Publicado em: Elsevier, 2010-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The mechanism for sustained Ca2+ influx activated by G protein-coupled receptors was examined. In Chinese hamster ovary cells expressing recombinant human endothelin type B receptor (ETBR) and endogenous P2Y receptor (P2Y-R), endothelin-1 elicited a sustained Ca2+ influx depending on Gq/11 protein,...