A novel orthotopic mouse model replicates human lung cancer cachexia

• Main Authors: Wouter R.P.H. van deWorp (Author), Jan Theys (Author), Alba Sanz González (Author), Brent van derHeyden (Author), Frank Verhaegen (Author), Duncan Hauser (Author), Florian Caiment (Author), Hubertus J.M. Smeets (Author), Annemie M.W.J. Schols (Author), Ardy vanHelvoort (Author), Ramon C.J. Langen (Author)
• Format: Book
• Published: Wiley, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Introduction Cancer cachexia, highly prevalent in lung cancer, is a debilitating syndrome characterized by involuntary loss of skeletal muscle mass and is associated with poor clinical outcome, decreased survival and negative impact on tumour therapy. Various lung tumour‐bearing animal mode...