(±)-5-bromo-2-(5-fluoro-1-hydroxyamyl) Benzoate Protects Against Oxidative Stress Injury in PC12 Cells Exposed to H2O2 Through Activation of Nrf2 Pathway

• Main Authors: Saidan Qi (Author), Xiaojiao Zhang (Author), Zhenzhen Fu (Author), Anran Pi (Author), Feiyan Shi (Author), Yanan Fan (Author), Jiahua Zhang (Author), Tingting Xiao (Author), Dong Shang (Author), Meng Lin (Author), Na Gao (Author), Junbiao Chang (Author), Yuan Gao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Oxidative stress is associated with the pathogenesis of ischemic stroke (±)-5-bromo-2-(5-fluoro-1-hydroxyamyl) benzoate (BFB) is a novel compound modified by dl-3-n-butylphthalide (NBP). Here, we hypothesized that BFB may protect the PC12 cells against H2O2-induced oxidative stress injur...