Reversible Oxidative Modifications in Myoglobin and Functional Implications

• Main Authors: Mark H. Mannino (Author), Rishi S. Patel (Author), Amanda M. Eccardt (Author), Blythe E. Janowiak (Author), David C. Wood (Author), Fahu He (Author), Jonathan S. Fisher (Author)
• Format: Book
• Published: MDPI AG, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Myoglobin (Mb), an oxygen-binding heme protein highly expressed in heart and skeletal muscle, has been shown to undergo oxidative modifications on both an inter- and intramolecular level when exposed to hydrogen peroxide (H₂O₂) in vitro. Here, we show th...