The Tetramethylpyrazine Derivative Statmp-151: A Novel Small Molecule Stat3 Inhibitor With Promising Activity Against Breast Cancer

• Main Authors: Chen Fan (Author), Yijie Wang (Author), Hui Huang (Author), Wenzhen Li (Author), Jialin Ma (Author), Dongping Yao (Author), Zijun Tang (Author), Taixiong Xue (Author), Liyang Ha (Author), Yan Ren (Author), Yiwen Zhang (Author), Qin Wang (Author), Yongmei Xie (Author), Yi Luo (Author), Rui Tan (Author), Jian Gu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Breast cancer is the most common malignancy in women and is a molecularly heterogeneous disease. Signal transducer and activator of transcription 3 (Stat3) is overexpressed and hyperactivated in a variety of human tumours, including breast cancer, thus representing a promising target for breast canc...