Overexpression of miR-506-3p reversed doxorubicin resistance in drug-resistant osteosarcoma cells

• Main Authors: Xinru Wang (Author), Rumeng Ding (Author), Zhe Fu (Author), Meng Yang (Author), Duolu Li (Author), Yubing Zhou (Author), Chongzhen Qin (Author), Wenda Zhang (Author), Liuzhe Si (Author), Jingmin Zhang (Author), Yuna Chai (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and objective: Osteosarcoma is a common primary malignant tumor of bone, and doxorubicin is one of the most widely used therapeutic drugs. While the problem of doxorubicin resistance limits the long-term treatment benefits in osteosarcoma patients. The role of miRNAs and their target gene...