Design, Development, Evaluation, and In Vivo Performance of Buccal Films Embedded with Paliperidone-Loaded Nanostructured Lipid Carriers

• Main Authors: Fahad Mohammed AlMulhim (Author), Anroop B. Nair (Author), Bandar Aldhubiab (Author), Hiral Shah (Author), Jigar Shah (Author), Vivek Mewada (Author), Nagaraja Sreeharsha (Author), Shery Jacob (Author)
• Format: Book
• Published: MDPI AG, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The therapeutic effectiveness of paliperidone in the treatment of schizophrenia has been limited by its poor oral bioavailability; hence, an alternative route could be appropriate. This study investigates the feasibility of developing a buccal film impregnated with paliperidone-loaded nanostructured...