Non-cytotoxic nanoparticles re-educating macrophages achieving both innate and adaptive immune responses for tumor therapy

• Main Authors: Shengmei Wang (Author), Xuanjun Liu (Author), Minghua Yang (Author), Linqi Ouyang (Author), Jinsong Ding (Author), Shengfeng Wang (Author), Wenhu Zhou (Author)
• Format: Book
• Published: Elsevier, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Macrophages are important antigen-presenting cells to combat tumor via both innate and adaptive immunity, while they are programmed to M2 phenotype in established tumors and instead promote cancer development and metastasis. Here, we develop a nanomedicine that can re-educate M2 polarized macrophage...