RNA-binding protein MEX3A controls G1/S transition via regulating the RB/E2F pathway in clear cell renal cell carcinoma

• Main Authors: Yuntan Qiu (Author), Meng Meng (Author), Chuanzhen Cao (Author), Jingyuan Zhang (Author), Xu Cheng (Author), Yongxin Huang (Author), Haotian Cao (Author), Yun Li (Author), Duanqing Tian (Author), Yongsheng Huang (Author), Li Peng (Author), Kaishun Hu (Author), Yin Zhang (Author), Jianyou Liao (Author), Jiehua He (Author), Xiaochun Wang (Author), Daning Lu (Author), Lehang Lin (Author), Xingang Bi (Author), Dong Yin (Author)
• Format: Book
• Published: Elsevier, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

MEX3A is an RNA-binding protein that mediates mRNA decay through binding to 3' untranslated regions. However, its role and mechanism in clear cell renal cell carcinoma remain unknown. In this study, we found that MEX3A expression was transcriptionally activated by ETS1 and upregulated in clear...