Design, synthesis, characterization and antidiabetic evaluation of 3,5-substituted thiazolidinediones: Evidenced by network pharmacology, Molecular docking, dynamic simulation, in vitro and in vivo assessment

In search of new antidiabetic agents, heterocyclic compounds containing 3,5-Substituted thiazolidinedione moieties were synthesized through a concise three-step reaction process. The synthesis involved Knoevenagel condensation at the 5th position of the 3,5-Substituted thiazolidinedione ring-system...

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Main Authors: Shankar Gharge (Author), Shankar G. Alegaon (Author), Swaroop Jadhav (Author), Shriram D. Ranade (Author), Rohini S. Kavalapure (Author)
Format: Book
Published: Elsevier, 2024-12-01T00:00:00Z.
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