Metallothionein-3 is a multifunctional driver that modulates the development of sorafenib-resistant phenotype in hepatocellular carcinoma cells

• Main Authors: Miguel Angel Merlos Rodrigo (Author), Hana Michalkova (Author), Ana Maria Jimenez Jimenez (Author), Frantisek Petrlak (Author), Tomas Do (Author), Ladislav Sivak (Author), Yazan Haddad (Author), Petra Kubickova (Author), Vivian de los Rios (Author), J. Ignacio Casal (Author), Marina Serrano-Macia (Author), Teresa C. Delgado (Author), Loreto Boix (Author), Jordi Bruix (Author), Maria L. Martinez Chantar (Author), Vojtech Adam (Author), Zbynek Heger (Author)
• Format: Book
• Published: BMC, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background & aims Metallothionein-3 (hMT3) is a structurally unique member of the metallothioneins family of low-mass cysteine-rich proteins. hMT3 has poorly characterized functions, and its importance for hepatocellular carcinoma (HCC) cells has not yet been elucidated. Therefore, we i...