Inactivated rabies vaccines: Standardization of an in vitro assay for residual viable virus detection.

• Main Authors: Beatriz Lourenço Correia Moreira (Author), Ana Paula Lappas Gimenez (Author), Jorge Minor Fernandes Inagaki (Author), Sonia Mara Raboni (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Human rabies, a neglected viral zoonosis, is preventable through domestic animals vaccination and post-exposure prophylaxis using inactivated rabies vaccines. During vaccine production, several mandatory in vivo quality control trials, such as potency, live virus, and safety, are responsible for the...