Management of Adverse Events in Cancer Patients Treated With PD-1/PD-L1 Blockade: Focus on Asian Populations

• Главные авторы: Jiqiao Yang (Автор), Xiujing He (Автор), Qing Lv (Автор), Jing Jing (Автор), Hubing Shi (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2019-07-01T00:00:00Z.
• Предметы: article
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The interaction between programmed cell death protein 1 (PD-1) and its ligand programmed death-ligand 1 (PD-L1) induces exhaustions of cytotoxic lymphocytes in the tumor microenvironment, which facilitates tumor immune evasion. PD-1/PD-L1 blockade therapy, which prevents the receptors and ligands fr...