Fentanyl enhances immune cell response through TLR4/MD-2 complex

Fentanyl enhances immune cell response through TLR4/MD-2 complex

IntroductionOpioids have been shown to induce neuroinflammation and immune cell activation, that might contribute to some of the opioid side effects, such as opioid-induced tolerance and paradoxical hyperalgesia. In this context, TLR4/MD-2 complex has been proposed as an off-target site for opioid a...

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Main Authors: Chiara Chemello (Author), Laura Facci (Author), Emma Marcolin (Author), Giovanni Eugenio Ramaschi (Author), Massimo Barbierato (Author), Pietro Giusti (Author), Chiara Bolego (Author), Morena Zusso (Author)
Format: Book
Published: Frontiers Media S.A., 2024-10-01T00:00:00Z.
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