MiR-146b-5p targets IFI35 to inhibit inflammatory response and apoptosis via JAK1/STAT1 signalling in lipopolysaccharide-induced glomerular cells

• Main Authors: Li-Hua Zhang (Author), Sheng-Zhi Jiang (Author), Xia Guo (Author), Bin Xiao (Author), Qiao Li (Author), Jian-Ying Chen (Author), Jie-Rou Huang (Author), Hui Rao (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The dysregulated microRNAs (miRNAs) are implicated in the malignancy of lupus nephritis (LN). This work aims to analyse the effect and mechanism of miR-146b-5p in lipopolysaccharides (LPS)-induced model of LN in vitro. The serum samples of LN patients and normal volunteers were collected. HK-2 cells...