The Encapsulation of Febuxostat into Emulsomes Strongly Enhances the Cytotoxic Potential of the Drug on HCT 116 Colon Cancer Cells

• Main Authors: Usama A. Fahmy (Author), Hibah M. Aldawsari (Author), Shaimaa M. Badr-Eldin (Author), Osama A. A. Ahmed (Author), Nabil A. Alhakamy (Author), Helal H. Alsulimani (Author), Filippo Caraci (Author), Giuseppe Caruso (Author)
• Format: Book
• Published: MDPI AG, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Febuxostat (FBX) is a drug able to inhibit xanthine oxidase and reduce uric acid production commonly used for the treatment of hyperuricemia in subjects suffering from gout. Several studies have also been directed at its use as anti-cancer drug during the last years, opening a window for its off-lab...