Screening of Biomarkers and Toxicity Mechanisms of Rifampicin-Induced Liver Injury Based on Targeted Bile Acid Metabolomics

Rifampicin (RIF) is a critical first-line drug for tuberculosis. However, long-term or high-dose treatment with RIF can induce severe liver injury; the underlying mechanism of this effect has not yet been clarified. This study was performed to screen reliable and sensitive biomarkers in serum bile a...

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Main Authors: Yang Deng (Author), Xilin Luo (Author), Xin Li (Author), Yisha Xiao (Author), Bing Xu (Author), Huan Tong (Author)
Format: Book
Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
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