Alanine Aminotransferase as a Monitoring Biomarker in Children with Nonalcoholic Fatty Liver Disease: A Secondary Analysis Using TONIC Trial Data

• Main Authors: Idil Arsik (Author), Jennifer K. Frediani (Author), Damon Frezza (Author), Wen Chen (Author), Turgay Ayer (Author), Pinar Keskinocak (Author), Ran Jin (Author), Juna V. Konomi (Author), Sarah E. Barlow (Author), Stavra A. Xanthakos (Author), Joel E. Lavine (Author), Miriam B. Vos (Author)
• Format: Book
• Published: MDPI AG, 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Validated noninvasive biomarkers to assess treatment response in pediatric nonalcoholic fatty liver disease (NAFLD) are lacking. We aimed to validate alanine aminotransferase (ALT), a monitoring biomarker for change in liver histology. Methods: A retrospective analysis using data from th...