Adsorption of Phenazines Produced by <i>Pseudomonas aeruginosa</i> Using AST-120 Decreases Pyocyanin-Associated Cytotoxicity

• Main Authors: Hidetada Hirakawa (Author), Ayako Takita (Author), Motoyuki Uchida (Author), Yuka Kaneko (Author), Yuto Kakishima (Author), Koichi Tanimoto (Author), Wataru Kamitani (Author), Haruyoshi Tomita (Author)
• Format: Book
• Published: MDPI AG, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

AST-120 (Kremezin) is used to treat progressive chronic kidney disease by adsorbing uremic toxin precursors produced by the gut microbiota, such as indole and phenols. Previously, we found that AST-120 decreased drug tolerance and virulence in <i>Escherichia coli</i> by adsorbing indole....