Neutrophil-Derived IL-6 Potentially Drives Ferroptosis Resistance in B Cells in Lupus Kidney

• Main Authors: Zechen Wang (Author), Jiajia Shen (Author), Kun Ye (Author), Jingjie Zhao (Author), Shaoang Huang (Author), Siyuan He (Author), Yujuan Qin (Author), Lingzhang Meng (Author), Jie Wang (Author), Jian Song (Author)
• Format: Book
• Published: Hindawi Limited, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ferroptosis resistance is vital for B cell development, especially in inflammatory diseases, yet the underlying mechanism is still unclear. In this study, based on the scRNA-seq technique and flow cytometry, we discovered a proportion of neutrophils exhibited upregulated expression of the IL-6 and c...