Cytotoxicity towards Breast Cancer Cells of Pluronic F-127/Hyaluronic Acid Hydrogel Containing Nitric Oxide Donor and Silica Nanoparticles Loaded with Cisplatin

• Egile Nagusiak: Bianca de Melo Santana (Egilea), Joana Claudio Pieretti (Egilea), Rafael Nunes Gomes (Egilea), Giselle Cerchiaro (Egilea), Amedea Barozzi Seabra (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2022-12-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

The incorporation of both nitric oxide (NO) donor (S-nitrosoglutathione, GSNO) and silica nanoparticles loaded with cisplatin (SiO₂@CisPt NPs) into a polymeric matrix represents a suitable approach to creating a drug-delivery system with sustained and localized drug release ag...