Novel Natrosol/Pectin-co-poly (acrylate) based pH-responsive polymeric carrier system for controlled delivery of Tapentadol Hydrochloride

• Main Authors: Nadiah Zafar (Author), Asif Mahmood (Author), Sehar Ilyas (Author), Hira Ijaz (Author), Rai Muhammad Sarfraz (Author), Wael A. Mahdi (Author), Mounir M. Salem-Bekhit (Author), Mohamed A. Ibrahim (Author), Yacine Benguerba (Author), Barbara Ernst (Author)
• Format: Book
• Published: Elsevier, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background & Objectives: This study aimed to create a controlled delivery system for Tapentadol Hydrochloride by developing interpenetrating networks (IPNs) of Natrosol-Pectin copolymerized with Acrylic Acid and Methylene bisacrylamide, and to analyze the effects of various ingredients on the ph...