Diacerein Inhibits Myopia Progression through Lowering Inflammation in Retinal Pigment Epithelial Cell

• Main Authors: Peng-Tai Tien (Author), Chia-Hung Lin (Author), Chih-Sheng Chen (Author), Ching-Yao Chang (Author), Hsiangyu Ku (Author), Dekang Gan (Author), Yi-Yu Tsai (Author), Jamie Jiin-Yi Chen (Author), Hui-Ju Lin (Author), Lei Wan (Author)
• Format: Book
• Published: Hindawi Limited, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Myopia is a highly prevalent refractive disorder. We investigated the effect of diacerein on monocular form deprivation (MFD) in hamsters as a possible therapeutic intervention. Diacerein is an anthraquinone derivative drug whose active metabolite is rhein. Diacerein or atropine was applied to the M...