Lignan-Rich Sesame (<i>Sesamum indicum</i> L.) Cultivar Exhibits In Vitro Anti-Cholinesterase Activity, Anti-Neurotoxicity in Amyloid-β Induced SH-SY5Y Cells, and Produces an In Vivo Nootropic Effect in Scopolamine-Induced Memory Impaired Mice

• Автори: Min-Young Kim (Автор), Sungup Kim (Автор), Jeongeun Lee (Автор), Jung-In Kim (Автор), Eunyoung Oh (Автор), Sang-Woo Kim (Автор), Eunsoo Lee (Автор), Kwang-Soo Cho (Автор), Choon-Song Kim (Автор), Myoung-Hee Lee (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2023-05-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Alzheimer's disease, a major cause of dementia, is characterized by impaired cholinergic function, increased oxidative stress, and amyloid cascade induction. Sesame lignans have attracted considerable attention owing to their beneficial effects on brain health. This study investigated the neuro...