Identification of the organic anion transporting polypeptides responsible for the hepatic uptake of the major metabolite of epyrifenacil, S‐3100‐CA, in mice

• Asıl Yazarlar: Kengo Sakurai (Yazar), Tomohiro Kuroda (Yazar), Jun Abe (Yazar), Hiroshi Toda (Yazar), Sachiko Kitamoto (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Wiley, 2021-10-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Epyrifenacil is a novel herbicide that acts as an inhibitor of protoporphyrinogen oxidase (PPO) and produces hepatotoxicity in rodents by inhibiting PPO. Our previous research revealed that the causal substance of hepatotoxicity is S‐3100‐CA, a major metabolite of epyrifenacil, and that hum...