Radiosynthesis and Radiotracer Properties of a 7-(2-[18F]Fluoroethoxy)-6-methoxypyrrolidinylquinazoline for Imaging of Phosphodiesterase 10A with PET

• Main Authors: Detlef Briel (Author), Peter Brust (Author), Achim Hiller (Author), Gregor Schwan (Author), Aurélie Maisonial (Author), Matthias Scheunemann (Author), Steffen Fischer (Author), Winnie Deuther-Conrad (Author), Uta Funke (Author)
• Format: Book
• Published: MDPI AG, 2012-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Phosphodiesterase 10A (PDE10A) is a key enzyme of intracellular signal transduction which is involved in the regulation of neurotransmission. The molecular imaging of PDE10A by PET is expected to allow a better understanding of physiological and pathological processes related to PDE10A expression an...