Lack of association between the <it>GRP78 </it>polymorphisms in the promoter and 3' UTR and susceptibility to chronic HBV infection in a Chinese Han population

• Main Authors: Lin Sheng-Qu (Author), Wang Jin-Long (Author), Lin Marie CM (Author), Fan Wen-Guo (Author), Li Dong-Pei (Author), Zhu Xiao (Author), Huang Jian-Qing (Author), Kung Hsiang-Fu (Author)
• Format: Book
• Published: BMC, 2010-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Hepatitis B virus (HBV) infection causes large amount of unfolding or false-folding protein accumulation in the endoplasmic reticulum (ER), which in turn induces the expression of glucose-regulated protein 78 (GRP78). The aim in the...