The development and evaluation of hyaluronic acid coated mitochondrial targeting liposomes for celastrol delivery

• Main Authors: Simeng Xiao (Author), Siying Huang (Author), Xiaojing Yang (Author), Yujie Lei (Author), Mingxiang Chang (Author), Junjie Hu (Author), Yan Meng (Author), Guohua Zheng (Author), Xinyan Chen (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

AbstractIn order to precisely deliver celastrol into mitochondria of tumor cells, improve antitumor efficacy of celastrol and overcome its troublesome problems in clinical application, a novel multistage-targeted celastrol delivery system (C-TL/HA) was developed via electrostatic binding of hyaluron...