Dexmedetomidine and Fentanyl exhibit temperature dependent effects on human respiratory cilia.

• Main Authors: Nils eWelchering (Author), Sebastian eOchoa (Author), Xin eTian (Author), Richard eFrancis (Author), Maliha eZahid (Author), Ricardo eMunoz (Author), Cecilia W Lo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2015-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Dexmedetomidine (dex) is commonly used in intensive care due to its effective sedation and analgesia with few adverse effects and minimal respiratory depression. However, we recently observed that exposing mouse epithelial respiratory cells to dex decreased ciliary beat frequency (CBF),...