Improving the solubility, activity, and stability of reteplase using in silico design of new variants
Reteplase (recombinant plasminogen activator, r-PA) is a thrombolytic agent recombined from tissue-type plasminogen activator (t-PA), which has several prominent features such as strong thrombolytic ability and E. coli expressibility. Despite these outstanding features, it demonstrates reduced fibri...
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Format: | Book |
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Wolters Kluwer Medknow Publications,
2019-01-01T00:00:00Z.
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A1234.567 |
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