WTAP-mediated m6A modification of TRIM22 promotes diabetic nephropathy by inducing mitochondrial dysfunction via ubiquitination of OPA1

Objectives Diabetic nephropathy (DN) is one of the most serious microvascular complications of diabetes and is the most common cause of end-stage renal disease. Tripartite motif-containing (TRIM) proteins are a large family of E3 ubiquitin ligases that contribute to protein quality control by regula...

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Autores principales: Zeng Zhang (Autor), Fengzhu Zhou (Autor), Min Lu (Autor), Duanchun Zhang (Autor), Xinyi Zhang (Autor), Siyu Xu (Autor), Yanming He (Autor)
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Publicado: Taylor & Francis Group, 2024-12-01T00:00:00Z.
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